Current News

2018

MyoKardia

June 26, 2018 - MyoKardia Doses First Patient in Pivotal Phase 3 EXPLORER Trial of Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy                                                                                                                                                                                                              PDF   

Thermalin

June 22, 2018 -Thermalin Announces: Additional Closing on $21M Series A Preferred Financing to Support its Cleveland-based R&D Team                   PDF   

MyoKardia

May 21, 2018 - MyoKardia Announces Design of Phase 3 EXPLORER-HCM Study Evaluating Mavacamten in Symptomatic, Obstructive Hypertrophic Cardiomyopathy                                                                                                                                                                                                                    PDF   

May 10, 2018 - MyoKardia Doses First Patient in PIONEER Open-Label Extension Study of Mavacamten for Symptomatic, Obstructive Hypertrophic Cardiomyopathy                                                                                                                                                                                                                     PDF   

April 2, 2018 - MyoKardia Begins Dosing in Phase 2 MAVERICK-HCM Clinical Trial of Mavacamten in Symptomatic Non-obstructive Hypertrophic Cardiomyopathy Patients Topline Data Anticipated in Second Half of 2019                                                                                                                            PDF   

March 11, 2018 - MyoKardia Announces Positive Results from Low-Dose Cohort of Phase 2 PIONEER-HCM Study of Mavacamten in Symptomatic, Obstructive Hypertrophic Cardiomyopathy Patients                                                                                                                                                        PDF   

March 8, 2018 - MyoKardia Reports Fourth Quarter and Full Year 2017 Financial Results                                                                                                   PDF   

February 14, 2018 - MyoKardia Begins Patient Dosing in Phase 1b Clinical Study of MYK-491 in Dilated Cardiomyopathy Patients                                 PDF   

2017

November 15, 2017 - Preclinical Studies with MyoKardia’s Mavacamten Demonstrate Evidence of Reduced Contractility and Improved Left Ventricular Compliance                                                                                                                                                                                                                     PDF   

November 13, 2017 - MyoKardia Presents Data from Study of Machine Learning Algorithm Intended to Identify Obstructive Hypertrophic Cardiomyopathy Using a Wearable Biosensor                                                                                                                                                               PDF   

November 2, 2017 - MyoKardia Reports Third Quarter 2017 Financial Results and Operational Progress                                                                 PDF   

November 1, 2017 - MyoKardia Announces Presentations at 2017 American Heart Association Scientific Sessions                                                    PDF   

DiCE Molecules 

December 19, 2017 -  DiCE Molecules Announce Multi-Year Research Collaboration with Genentech                                                                      PDF   

Warp Drive Bio

October 16, 2017 -Warp Drive Bio Forms Strategic Collaboration to Advance Novel Classes of Antibiotics to Combat Multi-Drug-Resistant Bacterial Infections PDF   

Thermalin

September 28, 2017 - Thermalin Announces:Collaboration with Sanofi to Develop Next Generation Insulin Therapies                                              PDF   

MyoKardia

September 27, 2017 -  MyoKardia Provides Update on MYK-491 Clinical Progress. Single Ascending Dose Trial in Healthy Volunteers Continues Enrollment in Order to Refine Exposure-Activity-Relationship; Topline Data Expected by Early 2018                                                                            PDF   

September 19, 2017 -MyoKardia Presents Additional Positive Data from Phase 2 PIONEER-HCM Study of Mavacamten (Formerly MYK-461) at the Heart Failure Society of America’s 21st Annual Scientific Meeting                                                                                                                                PDF   

August 7, 2017 - MyoKardia Reports Positive Topline Results in Phase 2 PIONEER-HCM Study of Mavacamten (Formerly MYK-461) in Symptomatic, Obstructive Hypertrophic Cardiomyopathy                                                                                                                                                                       PDF     

August 7, 2017 - MyoKardia Reports Second Quarter 2017 Financial Results and Operational Progress                                                                        PDF   

April 18, 2017 - MyoKardia Appoints David Meeker, M.D., to Board of Directors                                                                                                             PDF  

Warp Drive Bio

March 29, 2017 - Warp Drive Bio Forms Technology Alliance with GSK to Discover Potential Therapeutics in Oncology and Other Diseases                    PDF 

MyoKardia

March 17, 2017 - MyoKardia Appoints Kim Popovits and Wendy Yarno to Board of Directors                                                                                        View PDF 

March 13, 2017 - MyoKardia Reports Fourth Quarter and Full Year 2016 Financial Results and Operational Progress                                                        View PDF 

February 2, 2017 - First Subjects Dosed in Phase 1 Study of Dilated Cardiomyopathy Candidate MYK-491                                                                  View PDF 

January 3, 2017 - MyoKardia Announces Advancement to Next Phase of Global Collaboration with Sanofi                                                                  View PDF 

2016

MyoKardia

December 2, 2016 - MyoKardia Announces Receipt of Milestone Payment from Sanofi for DCM Candidate MYK-491

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December 1, 2016 - MyoKardia Announces Appointment of Marc Semigran, M.D., as Chief Medical Officer

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 Warp Drive Bio

November 29, 2016 - Warp Drive Bio Achieves Key Milestone in Antibiotics Collaboration with Sanofi 

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 MyoKardia

November 11, 2016 - MyoKardia Announces Exploratory Digital Health Substudy as Part of PIONEER-HCM Trial of MYK-461 in Symptomatic, Obstructive Hypertrophic Cardiomyopathy Patients

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November 7, 2016 - MyoKardia Reports Progress on Clinical Programs and Third Quarter 2016 Financial Results                                                      View PDF

November 2, 2016 - MyoKardia Announces Dosing of First Patient in Phase 2 PIONEER-HCM Study of MYK-461 in Symptomatic, Obstructive Hypertrophic Cardiomyopathy 

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September 21, 2016 - MyoKardia Outlines Path to Registration for MYK-461 in Symptomatic, Obstructive Hypertrophic Cardiomyopathy Patients and Provides Pipeline and Research Updates at Inaugural R&D Day

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Warp Drive Bio

August 30, 2016 - Warp Drive Bio Awarded Patent Covering Proprietary Method for Discovering New Medicines

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MyoKardia

July 11, 2016 - MyoKardia Announces Topline Clinical Data Supporting Advancement of MYK-461 to Phase 2 Pioneer-HCM study in Symptomatic, Obstructive Hypertrophic Cardiomyopathy Patients

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MyoKardia

June 1, 2016 - Study of SHaRE Data Published in PNAS Demonstrates the Power of Combining Clinical, Genetic, and Structural Data to Gain Insight into HCM

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May 2, 2016- MyoKardia Receives Orphan Drug Designation for MYK-461 for Treatment of Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)

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April 13, 2016- MyoKardia Names Mary Cranston to Board of Directors

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Warp Drive Bio

April 6, 2016 - Warp Drive Bio Appoints Alan C. Rigby, Ph.D., as Chief Scientific Officer

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DiCE

March 16, 2016 - Sanofi and DiCE Molecules Announce Research Collaboration to Discover Potential Therapeutics Based on Unique Small Molecule Discovery Platform  

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MyoKardia

February 4, 2016 - MyoKardia Publishes Article in Science Demonstrating That MYK-461 Prevents and Reverses Disease in Genetic Mouse Models of Hypertrophic Cardiomyopathy

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Warp Drive Bio

January 11, 2016 - Sanofi and Warp Drive Bio to Collaborate on the Development of Novel Oncology Therapies and Antibiotics Based on Proprietary Platforms 

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